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A wound is considered a complicated problem. Treatment efficiency depends on various aspects, including patient comorbidities, diagnosis, physiological condition, anatomical placement, and wound size. Consequently, the general guideline is that dressing selection is customized to the wound and cancer patient, with the direction and attention of physicians with wound treatment experience [ 12, 13]. This would support patients in receiving the appropriate treatment, achieving maximum efficiency, and avoiding adverse reactions during treatment. Traditional medicines have been used to treat moist desquamation and improve cancer patients’ quality of life. In a study, Erhe Gao cream was prepared using a Chinese medicine formula comprising calamine powder, zinc oxide powder, and lithospermum oil and was carefully applied to the affected skin daily. Traditional medicine effectively prevented the formation of moist desquamation, and the recovery time was 14 days [ 23]. Nigella sativa L. extract was used to evaluate the activity of avoiding the chance of acute radiation dermatitis in cancer cases. The applied gel delayed the onset of moist desquamation and acted as a pain-relieving material in breast cancer patients [ 24]. A flavonoid compound, silymarin, was extracted from Silybum marianum, and its role in preventing radiodermatitis in breast cancer patients was tested. A total of 40 patients undergoing radiotherapy were selected, and the gel was applied for five weeks continuously. Applying silymarin gel delayed and decreased the severity of radiodermatitis [ 25]. The nano-curcumin capsules were used to study the impact on radiotherapy-mediated skin damage.When compared to the control group, simultaneous administration of the nano-curcumin supplement did not substantially lower radiation-induced skin reaction severity (p > 0.05); however, there was a significant difference at week seven (p = 0.01). Moreover, patient-reported pain was considerably lower in the treatment group compared to the control group. Administering nano-curcumin possibly reduced radiation-induced skin damage in breast cancer patients. However, this benefit was not statistically significant [ 26]. Wound dressing is an excellent strategy for wound care and therapy, as evidenced by the favorable findings of various trials. However, further research and development are needed to validate modern dressing methods. Currently available dressing methods are critical to establishing a moist environment for wound healing, pain relief, and antibacterial protection. Unfortunately, only a few clinical trials have been conducted to assess the efficacy of these popular modern dressings. Trials on wound dressing effectiveness are typically performed on less complicated wounds, resulting in oversimplification of the actual clinical aspects.
Mepitel Dressing | Mepitel Wound Contact Layer Dressings
Schematic representation of some dressings utilized in the prevention and treatment of acute radiation dermatitis. When used on bleeding wounds or wounds with high viscosity exudate, Mepitel should be covered with a moist absorbent dressing pad. Safetac also protects new tissue and intact skin, so wounds remain undisturbed to support faster healing. Mepitel One seals the wound margins to protect skin from damaging leaks and maceration. When used after facial resurfacing, avoid placing pressure upon the dressing. Lift and reposition the dressing at least every second day. The wound should be inspected for signs of infection according to clinical practice. Consult a health care professional for the appropriate medical treatment.Mepitel used after facial resurfacing: avoid placing pressure upon the dressing lift and reposition the dressing at least every second day. When used on bleeding wounds or wounds with high-viscosity exudate, Mepitel® One should be covered with a moist, absorbent dressing pad. Acute radiodermatitis is defined by skin lesions that appear within 90 days of radiotherapy. During the first week of radiotherapy, acute radiodermatitis (Grade 1) may cause mild and transient redness on the skin (erythema). By the second week, dryness and peeling (desquamation) may occur due to dehydration in Grade 2. Within three to six weeks, severe pain and moist peeling (desquamation) may develop in Grade 3 dermatitis. Chronic radiodermatitis develops more than 90 days after the completion of radiation treatment. In some cases, it may occur after six months or years after irradiation. Symptoms such as dermal necrosis, keratoses, edema, fibrosis, dermal sclerosis, pigmentation, epidermal or dermal atrophy, vascular injury, and telangiectasia are common. Modified from Iacovelli et al. [ 33]. When used on burns treated with meshed grafts or after facial resurfacing, imprints can occur if the product is not used properly. Edwards J, Mason S (2013) Hand burn management: minimizing pain and trauma at dressing change. Br J Nurs 2(20): S46-S50
Mepitel One gentle wound contact layer | Mölnlycke Mepitel One gentle wound contact layer | Mölnlycke
Further clinical studies and research are required to establish the safety and efficacy of several types of latest wound dressing methods. Analyzing novel materials for modern wound dressings with positive outcomes exhibited via numerous tests has resulted in innovation in enhancing the dressing materials available in the market. The recent trend in developing ideal dressing products has several advantages. It has various health benefits, including increased antibacterial activities, environmental benefits, high biological compatibility, eco-friendly, and ease of handling, especially with natural polymers. New materials have been designed to respond to the various situations and stages of wound healing. Waring M, Bielfeldt S, Mätzold K, Wilhelm KP, Butcher M (2011) An evaluation of the skin stripping of wound dressing adhesives. J Wound Care 20(9): 412-422 There are various choices available, including hydrogels made from biopolymers. Notably, there have been significant advancements in traditional medicine, film dressings, stem cells, and growth factors used for radiation-induced dermatitis. Safetac also protects new tissue and intact skin – so wounds remain undisturbed to support faster natural healing . And it seals the wound margins to protect skin from damaging leaks and maceration . This silver foam dressing can inactivate wound relevant pathogens (bacteria and fungi) within 30 minutes, as shown in vitro . An international consensus has concluded that an antimicrobial action is indicated to help reduce bioburden in infected wounds and acts as an antimicrobial barrier in wounds at high risk of infection or re-infection .Soft, thin, breathable and waterproof film is highly conformable and contributes to optimum patient protection & comfort Mepitel is clinically provento heal scalds faster and with less pain and cost, compared to silver sulfadiazine Mepitel is clinically provento enable faster healing with less pain and cost, compared to silver sulfadiazine
Mepitel Wound Contact Layer Dressing - MedicalDressings Mepitel Wound Contact Layer Dressing - MedicalDressings
The nature of the bond that forms between Mepitel and the skin surface is such that the dressing can be removed with minimum pain and without damaging delicate new tissue. Mepitel One has an open mesh structure that allows exudate to pass through into a secondary absorbent dressing and enables the delivery of topical treatments. Mepitel One allows secondary dressings to be changed without disturbing the wound bed. Our thin Mepitel Film design is very conformable and adapts well to surface irregularities and different body contours. It provides a flexible transparent covering, to protect your patient's skin or wound from microbial contamination, fluid strikethrough, or other external contamination.
The design includes a Safetac ® interface which seals the wound edges, preventing the exudate to leak onto the surroundingskin, thus minimising the risk for maceration . Safetac interface also minimises damaging the wound or surrounding skin orexposing the patient to additional pain at dressing changes . Since its launch in 2009, a number of studies have highlighted the benefits of using Mepitel ® One. Safetac also protects new tissue and intact skin, so wounds remain undisturbed, to support faster healing. Mepitel seals the wound margins to protect skin from damaging leaks and maceration.
Mepitel® Soft Silicone Wound Contact Layer | Wound Dressings Mepitel® Soft Silicone Wound Contact Layer | Wound Dressings
When using for the fixation of skin grafts and protection of blisters, the dressing should not be changed before the fifth day post application Mepitel ® Film is designed to protect fragile and sensitive skin and minimise risk of skin breakdown . You can use this gentle breathable film as an only dressing or in combination with other products.
Collin O (2009) Use of Mepitel One dressing following hand surgery: a case study series. Poster presentation. Wounds UK Conference, United Kingdom Collin (2009) describes the use of Mepitel ® One following hand surgery in a non-comparative, ten patient case series. The author found dressing conformability was rated by the investigator as ‘good’ to ‘very good’; handling at application and ease of removal were generally rated as ‘easy’ to ‘very easy’. The patients also rated dressing conformability and comfort as ‘good’ to ‘very good’. No pain was associated with the removal of the Mepitel One dressings. There were no reports of leakage or dressing displacement. All wounds responded well and were associated with, at worst, minimal bleeding or exudation (as would be expected of this type of wound). No odour or signs of infection/ inflammation were reported. The condition of the peri-wound skin was generally healthy although mild maceration developed around one of the wounds. If used on epidermolysis bullosa patients, employ extra surveillance at dressing changes. Adhesion level of Mepitel® One is somewhat higher than that of Mepitel®.
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